BDBM10620 (S)-3-(1-(dimethylamino)ethyl)phenyl ethyl(methyl)carbamate::3-((1S)-1-(Dimethylamino)ethyl)phenyl N-ethyl N-methyl carbamate::3-(1-(dimethylamino)ethyl)phenyl ethyl(methyl)carbamate::3-[(1S)-1-(dimethylamino)ethyl]phenyl N-ethyl-N-methylcarbamate::CHEMBL636::ENA-713::Ethyl-methyl-carbamic acid 3-((R)-1-dimethylamino-ethyl)-phenyl ester::Ethyl-methyl-carbamic acid 3-((S)-1-dimethylamino-ethyl)-phenyl ester::Ethyl-methyl-carbamic acid 3-(1-dimethylamino-ethyl)-phenyl ester::Exelon::Rivastigmine::Rivastigmine (1)::SDZ-212-713::SDZ-ENA-713
SMILES [H][C@@](C)(N(C)C)c1cccc(OC(=O)N(C)CC)c1
InChI Key InChIKey=XSVMFMHYUFZWBK-NSHDSACASA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 10620
Affinity DataIC50: 830nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:The reaction mixture containing phosphate buffer, AChE or BChE and chosen compounds was prepared and intensively stirred. In given times (5, 10, 15, ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:For rat AChE or BuChE inhibition assays, a reaction mixture (100 μL) containing acetylthiocholine iodide (1 mmol/L, 30 μL) (J&K Scientific)...More data for this Ligand-Target Pair
Affinity DataIC50: 7.72E+3nMpH: 8.0Assay Description:In vitro AChEI activity was performed based on the modified Ellman's methodas previously reported by our group using a 96-well plate reader (BioTek E...More data for this Ligand-Target Pair
Affinity DataIC50: 7.72E+3nMpH: 8.0 T: 2°CAssay Description:In vitro anti-AChE activity was performed based on the modified Ellman's method [Ellman et al., Biochem. Pharmacol., 71:88-95]. For this purpose, syn...More data for this Ligand-Target Pair
Affinity DataIC50: 3.84E+4nMAssay Description:The IC50 values were determined using the spectrophotometric Ellman's method. All of the tested compounds were dissolved in 0.01 M DMSO and then ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.25E+4nMAssay Description:The eight synthesized dialkyl-3-cyanopropylphosphates (3a-h) were dissolved in0.01 M dimethyl sulphoxide and then diluted in demineralized water to 1...More data for this Ligand-Target Pair
Affinity DataIC50: 370nMAssay Description:Inhibition of BChE in rat serum using butyrylthiocholine iodide substrate incubated for 15 mins by UV spectroscopy based Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.41E+3nMAssay Description:Inhibition of BChE in rat serum after 15 mins by modified Ellman methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.66E+3nMAssay Description:Inhibition of BChE in rat serum after 15 mins by modified Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:In vitro inhibitory concentration against butyrylcholinesterase was determined using rat serum homogenateMore data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Inhibition of equine BuChE after 120 mins by Ellman's methodMore data for this Ligand-Target Pair